Children born in the 1970s and 1980s received just a handful of vaccinations: measles, rubella, and a few others. Beginning the 1990s, the numbers of mandated vaccines exploded, so that today a fully-vaccinated child might receive almost three dozen vaccinations by the time he or she turns six. Worries over vaccinations are nothing new, but in recent years they have reached a new state of intensity. Supposed links between vaccinations and the spike in diagnoses of autism have generated a well-publicized anti-vaccination movement. Mark A. Largent addresses the roots of this controversy in Vaccine: The Debate in Modern America (Johns Hopkins University Press, 2012), a book that is as refreshing for its accessible, readable style as it is for the nuanced, dispassionate, and fair manner it treats the players in this debate, from health care professionals to Jenny McCarthy.